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e., Web) and serotonin (i.e, SERT). Mephedrone and methylone work as non-selective transporter substrates, thereby stimulating non-exocytotic launch of dopamine, norepinephrine and serotonin. In contrast, MDPV functions for a powerful blocker at DAT and Web, with very little outcome at SERT. Administration of mephedrone or methylone to rats increas